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At-Home Treatment of Lymphedema Clinical Trials & Evidence


Tactile Medical is a leader in developing clinical evidence to support the use of our products. We actively collaborate with medical professionals, researchers and industry groups and have a strong commitment to developing clinical evidence with nationally and internationally recognized clinicians and researchers.

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    Study/Article
    A prospective preliminary study to assess the comparative efficacy of varying treatment frequency and duration. Subjects were randomized to 3…
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    Study/Article

    Under Recognition and Treatment of Lymphedema in Head and Neck Cancer Survivors – A Database Study

    June 12, 2023 | Cancer-related lymphedema, Diagnostics and treatment
    A retrospective health care utilization(HCU) analysis of 16,654 patients diagnosed with cancer of the head and neck cancer (HNC) between…
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    Study/Article
    A prospective, randomized, proof-in-principle study to evaluate the effectiveness of Flexitouch Plus (FT) with conservative care to conservative care alone…
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    Study/Article
    A retrospective health care utilization (HCU) analysis of 60,284 patients with lymphedema comparing those determined to be severely obese (defined…
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    Study/Article

    The Journal of Venous Disease Expert Opinion Consensus on Lymphedema Diagnosis and Treatment

    March 17, 2022 | Diagnostics and treatment, Patient experience, Venous-related and primary lymphedema
    A panel of experts from the American Venous Forum (AVF), American Vein and Lymphatic Society (AVLS) and the Society for…
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    Study/Article
    Authors: Sheila H. Ridner, Mary S. Dietrich, Jie Deng, Sandra L. Ettema & Barbara Murphy Purpose: Lymphedema associated with head and neck cancer (HNC) therapy…
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    Study/Article

    Flexitouch for Head and Neck Lymphedema: A Randomized Control Trial

    June 02, 2020 | Cancer-related lymphedema, Diagnostics and treatment
    Overview of a Vanderbilt randomized control trial comparing use of the Flexitouch system plus self-management with self-management alone for treatment…
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    Study/Article

    Compression Devices for Head & Neck Lymphedema | Tactile Medical

    January 11, 2020 | Cancer-related lymphedema, Diagnostics and treatment
    Background Head and neck cancer (HNC) survivors experience head and neck lymphedema (HNL), which requires treatment to prevent morbidity. We…
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    Study/Article

    Flexitouch® System Stimulates Lymphatic Function for Head and Neck Cancer – Related Lymphedema Patients

    January 29, 2019 | Cancer-related lymphedema, Diagnostics and treatment
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    Study/Article
    Ten head and neck cancer survivors diagnosed with head and neck lymphedema (HNL) were imaged using near-infrared fluorescence lymphatic imaging…
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    Study/Article
    Authors: Michelle Lerman, Julia A. Gaebler, PhD, Sunday Hoy, Esq., Jessica Izhakoff, Laura Gullett, Timothy Niecko, MS, Pinar Karaca-Mandic, PhD,…
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    Study/Article

    RTC: Early Intervention Speeds Venous-Ulcer Healing

    March 24, 2018 | Venous-related and primary lymphedema
    The 2018 Early Venous Reflux Ablation (EVRA) trial evaluated the role of early endovenous treatment of superficial venous reflux as…
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    Study/Article
    Authors: Harvey N. Mayrovitz PhD, Shelly Ryan PT, CLT-LANA and James M. Hartman MD Published: Head & Neck: Journal of the…
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    Study/Article

    Flexitouch – The Cutaneous, Net Clinical and Health Economic Benefits of Advanced Pneumatic Compression Devices in Patients with Lymphedema

    October 01, 2015 | Cancer-related lymphedema, Diagnostics and treatment, Venous-related and primary lymphedema
    Download highlights Authors: Pinar Karaca-Mandic, PhD, Alan T. Hirsch, MD, Stanley Rockson, MD, and Sheila Ridner, PhD, RN Published: Journal of…
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    Study/Article

    Flexitouch – Pneumatic Compression Improves Quality of Life in Patients with Lower-Extremity Lymphedema

    May 01, 2015 | Diagnostics and treatment, Venous-related and primary lymphedema
    Authors: Sheila N. Blumberg, MD, MS, Todd Berland, MD, Caron Rockman, MD, Firas Mussa, MD, Allison Brooks, MSN, RN-BC, Neal…
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    Study/Article
    The lymphatic system—not the veins—is primarily responsible for returning capillary ultrafiltrate and plasma proteins to blood circulation. Review modern evidence…
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    Study/Article
    Authors: Satish C. Muluk, MD, Alan T. Hirsch, MD, and Elise C. Taffe, MD Published: European Journal of Vascular and Endovascular…
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    Study/Article
    Authors: Caroline E. Fife, MD, Suzanne Davey, OTR/L CLT-LANA, Erik Maus, MD, Renie Guilliod, MD, and Harvey N. Mayrovitz, PhD…
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    Study/Article
    Author: Tina Hammond, PTA, CLT-LANA, and Harvey N. Mayrovitz, PhD Published: Health Care Management Practice. 2010; Vol. 22: 397–402 ABSTRACT: The physiological…
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    Study/Article
    Authors: Kristen E. Adams, PhD, John C. Rasmussen, PhD, Chinmay Darne, PhD, I-Chih Tan, PhD, Melissa B. Aldrich, PhD, Milton…
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    Study/Article

    Flexitouch – Advanced Pneumatic Therapy in Self-Care of Chronic Lymphedema of the Trunk

    September 04, 2010 | Cancer-related lymphedema, Core/truncal edema, Diagnostics and treatment
    Authors: Sheila H. Ridner, PhD, RN, Barbara Murphy, MD, Kie Deng, PhD, RN, Nancy Kidd, BS, Emily Galford, RN, and…
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    Study/Article

    Flexitouch – Using a Programmable Pneumatic Device with Truncal Therapy to Facilitate Wound Healing: A Case Series

    December 04, 2009 | Core/truncal edema, Diagnostics and treatment, Venous-related and primary lymphedema
    Author: Caren Betz, PT Published: Ostomy Wound Management. 2009; Vol. 55(3): 34–40 ABSTRACT: A sequential intermittent pneumatic compression (IPC) device was evaluated…
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    Study/Article
    Author: Tina Hammond, PTA, CLT-LANA Published: The Open Rehabilitation Journal. 2009; Vol. 2: 59–62 ABSTRACT: Lymphedema is a chronic condition requiring multiple…
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    Study/Article

    Flexitouch – Can Truncal Edema be Treated with Pneumatic Compression?

    May 04, 2009 | Core/truncal edema, Diagnostics and treatment
    Author: Tina Hammond, PTA, CLT-LANA Published: National Lymphedema Network’s LymphLink. 2009; Vol. 21(2) ABSTRACT: A 44-year-old female patient received complete decongestive therapy…
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    Study/Article

    Flexitouch – Overcoming Barriers in the Management of Lower Extremity Lymphedema Utilizing Advanced Pneumatic Therapy

    February 04, 2009 | Diagnostics and treatment, Venous-related and primary lymphedema
    Authors: Tina Hammond, PTA, CLT-LANA, and Alison H. Golla, MA, OTR/L, CLT Published: The Open Rehabilitation Journal. 2009; Vol. 2: 79–85 ABSTRACT:…
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    Study/Article
    Author: Samantha Cannon, MSOT/L, CLT Published: Cases Journal. 2009; Vol. 2:6625 ABSTRACT: The two patients in this case series had experienced long-term…
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    Study/Article
    Author: Sonja M. Maul, CLT-LANA, Julie A. Devine, OTR/L, CLT, and Carolyn R. Wincer, PT, DPT, CLT-LANA Published: Medical Devices: Evidence and…
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    Study/Article

    Flexitouch – Home Based Lymphedema Treatment in Patients With and Without Cancer-Related Lymphedema

    July 01, 2008 | Cancer-related lymphedema, Diagnostics and treatment, Lymphedema basics
    Authors: Sheila Ridner, PhD, RN, Elizabeth McMahon, PhD, Mary Dietrich, PhD, and Sunday Hoy, Esq. Published: Oncology Nursing Forum. 2008; Vol.…
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    Study/Article
    Author: Harvey N. Mayrovitz, PhD Published: Physical Therapy. 2007; Vol. 87(10): 1379–1388 PURPOSE: Sequential compression is used to manage lymphedema, but…
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    Study/Article
    Authors: Olivia Wilburn, MD, PhD, Paul Wilburn, and Stanley G. Rockson, MD Published: BMC Cancer. 2006; Vol. 6(1): 84–89 PURPOSE: Prospective…
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